IMAGING SCIENCE AND PHOTOCHEMISTRY ›› 2023, Vol. 41 ›› Issue (5): 253-259.DOI: 10.7517/issn.1674-0475.230606

• Review and Articles • Previous Articles     Next Articles

Application Value of Ultramicro-Flow Imaging and Energy Doppler Ultrasound in the Diagnosis of Gouty Arthritis

CAO Yuying1, CAO Jianhua2, HOU Tingting1, SUN Mingli1, WANG Shuling1   

  1. 1. Ultrasound Department of The No.4 People's Hospital of Hengshui, Hengshui 053000, Hebei, P.R. China;
    2. Operating room of The Second People's Hospital of Hengshui, Hengshui 053000, Hebei, P.R. China
  • Received:2023-06-25 Online:2023-09-23 Published:2023-10-28

Abstract: Application value of ultramicro-flow imaging (SMI) and energy Doppler ultrasound (PDUS) in diagnosis of gouty arthritis. Ninety-eight patients with gouty arthritis were selected, all of which were given SMI and PDUS examination, and the blood flow classification of gouty stone and synovium hyperplasia in patients with different periods and levels of hypersensitive C-reactive protein (hs-CRP) was analyzed. The results showed that the ultrasonic imaging manifestations of gouty arthritis patients were joint effusion, multi-point hyperechoic, gouty stone, double-track sign and synovial thickening. The level of hs-CRP in 253patients with acute stage was higher than that in patients with remission stage (P<0.05). Compared with PDUS mode, there were more cases of high grade (2 and 3) and fewer cases of low grade (0 and 1) in SMI mode than in PDUS mode (P<0.05). Compared with patients in remission stage, patients in acute stage had higher grade (2 and 3) (P<0.05) and less low grade (0 and 1) (P<0.05) under different modes (gouty stone and synovial hyperplasia blood flow grade). In different modes (gout stone and synovium hyperplasia blood flow grades), the high grade (2 and 3) was more than that in the slightly increased hs-CRP group and the normal group (P<0.05), and the low grade (0 and 1) was less than that in the slightly increased hs-CRP group and the normal group (P<0.05). Spearman correlation analysis showed that there was a positive correlation between hs-CRP level and blood flow grading of gout stone and synovium hyperplasia under different modes (P<0.05), and the correlation between hs-CRP level and SMI mode grading was higher (P<0.05). Therefore, compared with PDUS, SMI can detect more blood flow signals in gouty arthritis (gout stone and synovium hyperplasia) and has a stronger correlation with hs-CRP levels, which is more conducive to reflecting the activity of patients with gouty arthritis.

Key words: super microvascular imaging, power Doppler ultrasound, gouty arthritis, gouty stone, synovial hyperplasia