Imaging Science and Photochemistry ›› 1991, Vol. 9 ›› Issue (2): 156-159.DOI: 10.7517/j.issn.1674-0475.1991.02.156

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THE ABILITY OF SOME HEMATOPORPHYRIN 3,8-ALKYLOXY (THIO) DERIVATIVE FOR PHOTO-GENERATING SINGLET OXYGEN

CHEN JI-YAO1, Lu YA-MENG1, CHEN SHI-MING1, CAI HUAI-XIN1, Xu DE-YU2, ZHANG HAO2   

  1. 1. Physics department. Analysis and measurement centre, Fudan University, Shanghai, 200433, P. R. China;
    2. Second Military Medical College, Shanghai, 200453, P. R. China
  • Received:1990-03-26 Revised:1990-10-08 Online:1991-05-20 Published:1991-05-20

Abstract: Photosensitization of some individual hematoporphyrin 3,8-alkyloxy (thio) derivatives was studied by ESR method. According to the increasing intensities of ESR signal of nitroxyl free radical products, the ability of these compounds, for photo-generting singlet oxygen was evaluated. The results shown that different hematoporphyrin derivative has considerable infuence on the sensitization abilities, which reveals a way to explore new porphyrin photosensitizer by changing its derivatives.

Key words: Hematoporphyrin derivative, electron spin resonance, singlet oxygen