Study on CEUS Characteristics and Parameter Changes in Patients with Thyroid Cancer

doi:10.7517/issn.1674-0475.220507

Abstract

Abstract: This study investigated the clinical value of contrast-enhanced ultrasound (CEUS) in the differential diagnosis of benign and malignant thyroid tumors, and judging whether thyroid cancer has lymph node metastasis and capsule invasion. 68 patients with confirmed thyroid cancer were selected as the thyroid cancer group and 70 patients with benign thyroid tumor as the control group. Both groups of patients underwent ultrasound and CEUS. The ultrasonic image characteristics, CEUS characteristics and parameter differences between the two groups were compared and analyzed. According to whether the thyroid cancer has envelope invasion and lymph node metastasis, the patients with thyroid cancer were stratified, and the differences of CEUS parameters were compared and analyzed. The proportion of patients with unclear boundary and aspect ratio ≥ 1 in thyroid cancer group was significantly higher than that in control group (P<0.05). The proportion of patients with unclear boundary, uneven enhancement mode and obvious early regression in thyroid cancer group was significantly higher than that in control group (P<0.05). The peak intensity (PI), time to peak (TTP) and mean transit time (MTT) of nodules in thyroid cancer group were significantly lower than those in control group (P<0.05). The PI, TTP and MTT values of thyroid cancer patients with lymph node metastasis were lower than those without lymph nodes (P<0.05). CEUS characteristic parameters and imaging features are of great value in differential diagnosis of benign and malignant thyroid tumors and in judging the degree of malignancy of thyroid cancer.

Key words: contrast-enhanced ultrasonography, differential diagnosis, thyroid cancer, benign and malignant, degree of malignancy

LI Mei, ZHENG Suili, LIU Chu, HUANG Yuechun. Study on CEUS Characteristics and Parameter Changes in Patients with Thyroid Cancer[J]. IMAGING SCIENCE AND PHOTOCHEMISTRY, 2022, 40(4): 773-777.

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