碳纳米管在电化学和光化学纳米生物传感器中的应用

doi:10.7517/j.issn.1674-0475.2011.01.70

影像科学与光化学 ›› 2011, Vol. 29 ›› Issue (1): 70-76.DOI: 10.7517/j.issn.1674-0475.2011.01.70

• 应用与发展 • 上一篇

碳纳米管在电化学和光化学纳米生物传感器中的应用

郝平, 高云燕, 欧植泽, 刘丽华, 王中丽, 殷卫峰

西北工业大学理学院应用化学系, 陕西西安 710072

收稿日期:2010-06-20 修回日期:2010-09-10 出版日期:2011-01-23 发布日期:2011-01-23
通讯作者: 高云燕,副教授,硕士生导师,E-mail:gaoyunyan@nwpu.edu.cn.
基金资助:
教育部留学回国人员科研启动基金(N9YK0003,N9YK0005);西北工业大学基础研究基金(NPU-FFR-JC200822);西北工业大学翱翔之星项目(R0120)资助项目

The Applications of Carbon Nanotubes in Electrical and Optical Nanobiosensor

HAO Ping, GAO Yun-yan, OU Zhi-ze, LIU Li-hua, WANG Zhong-li, YIN Wei-feng

Department of Applied Chemistry, School of Science, Northwestern Polytechnical University, Xi’an 710072, Shanxi, P. R. China

Received:2010-06-20 Revised:2010-09-10 Online:2011-01-23 Published:2011-01-23

摘要/Abstract

摘要： 碳纳米管(CNTs)因具有独特的物理化学及电化学性质,如较大的比表面积、较强的电子转移能力和良好的吸附性能等而引起人们的广泛关注.碳纳米管可以通过物理吸附、静电或疏水作用等非共价结合方式或共价连接方式固定生物大分子(如蛋白质、DNA、抗体等),有效地促进生物大分子与电极间直接、快速的电子转移,可应用于多种电化学生物传感器中.碳纳米管本身在近红外光区具有独特的荧光和拉曼光谱,可以利用多种光谱手段对多种生物分子实现定量检测,因此近年来碳纳米管在光化学生物传感器中的应用也逐渐受到了研究者的重视.本文对碳纳米管在电化学和光化学生物传感器中的应用进行了简要综述和展望.

关键词: 碳纳米管, 电化学传感器, 光化学传感器, 纳米生物技术

Abstract: Carbon nanotubes (CNTs) have attracted great attention in many fields due to their unique physical and electrochemical properties,such as large specific surface area,strong electron transfer capability,good adsorption performance,etc.Immobilization of enzymes,proteins,DNA and other biomacromolecules to the surface of carbon nanotubes can be achieved through covalent and non-covalent interactions,including physical absorption,electrostatic and hydrophobic interactions,which facilitates a direct,fast electron transfer from biomolecules to electrode and can be applied in electrochemical biosensors.On the other hand,carbon nanotubes have recently been applied in the design of optical biosensors.Multiple spectral estimation can be employed to quantitative analysis of the biological molecules,through mesurement of the characteritical Raman spectra and fluorescence emission of CNTs in near IR region.In this paper,the application of carbon nanotubes in the fields of electrical and optical biosensors are reviewed.

Key words: carbon nanotubes, electrical biosensor, optical biosensor, nano-biotechnology

中图分类号:

郝平, 高云燕, 欧植泽, 刘丽华, 王中丽, 殷卫峰. 碳纳米管在电化学和光化学纳米生物传感器中的应用[J]. 影像科学与光化学, 2011, 29(1): 70-76.

HAO Ping, GAO Yun-yan, OU Zhi-ze, LIU Li-hua, WANG Zhong-li, YIN Wei-feng. The Applications of Carbon Nanotubes in Electrical and Optical Nanobiosensor[J]. Imaging Science and Photochemistry, 2011, 29(1): 70-76.

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碳纳米管在电化学和光化学纳米生物传感器中的应用

The Applications of Carbon Nanotubes in Electrical and Optical Nanobiosensor

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