影像科学与光化学 ›› 2022, Vol. 40 ›› Issue (1): 48-52.DOI: 10.7517/issn.1674-0475.210728

• 综述与论文 • 上一篇    下一篇

彩超联合人绒毛膜促性腺激素β诊断早期宫外孕的研究

肖旭, 赵淑霞, 黄立   

  1. 北京怀柔医院妇产科, 北京 101400
  • 收稿日期:2021-07-22 发布日期:2022-01-11
  • 通讯作者: 肖旭

Study of Color Doppler Ultrasonography Combined with Human Chorionic Gonadotropin β in Diagnosis of Early Ectopic Pregnancy

XIAO Xu, ZHAO Shuxia, HAUNG Li   

  1. Obstetrics and Gynecology Department, Beijing Huairou Hospital, Beijing 101400, P. R. China
  • Received:2021-07-22 Published:2022-01-11

摘要: 本文探讨经阴道彩色多普勒超声、人绒毛膜促性腺激素β(β-hCG)在早期异位妊娠诊断中的价值。选取异位妊娠患者78例作为观察组,根据超声影像特征,其中环状征型、混合包块型和典型孕囊型分别为15例、24例和39例;选取正常妊娠者140例作为对照组。两组均行经阴道彩色多普勒超声检查,采用电化学发光法检查血清β-hCG水平。结果显示,与对照组比较,观察组子宫内膜厚度和血清β-hCG水平降低(P<0.05);环状征型、典型孕囊型和混合包块型患者血清β-hCG水平比较差异有统计学意义(P<0.05);血清β-hCG水平联合子宫内膜厚度预测异位妊娠的ROC曲线下面积为0.901(P<0.05)。经阴道彩色多普勒超声联合β-hCG在异位妊娠诊断中有较好的效果,同时异位妊娠患者β-hCG水平与彩超影像特征有一定关系。

关键词: 经阴道彩色多普勒超声, 人绒毛膜促性腺激素β, 异位妊娠, 临床意义

Abstract: This paper discussed the value of transvaginal color Doppler ultrasound combined with human chorionic gonadotropin β (β-hCG) in the diagnosis of early ectopic pregnancy. Seventy-eight patients with ectopic pregnancy were selected as observation group, according to the characteristics of ultrasound images, there were 15 cases of circular sign, 24 cases of mixed mass and 39 cases of typical gestational sac. A total of 140 cases of normal pregnancy were selected as the control group. Color Doppler ultrasound was performed in both groups,and the serum β-hCG level was examined by electrochemiluminescence. The endometrial thickness and serum -hCG leve of the observation group was significantly lower than that of the control group (P<0.05). There was significant difference in serum β-hCG levels among patients with ring sign, typical gestational sac and mixed mass (P<0.05).The area under ROC curve for serum β-hCG level combined endometrial thickness prediction of ectopic pregnancy was 0.901, respectively, P<0.05. Transvaginal color Doppler ultrasound combined with β-hCG in the diagnosis of ectopic pregnancy has a good effect, and ectopic pregnancy patients β-hCG level have a certain relationship with color Doppler ultrasound image characteristics.

Key words: transvaginal color Doppler ultrasound, human chorionic gonadotropin, ectopic pregnancy, clinical significance