Advances in Basic Application of Nano-sized Contrast Agents to Imaging Diagnosis of Tumors

doi:10.7517/issn.1674-0475.200818

Abstract

Abstract: The early diagnosis of tumors, which is crucial to patients' survival rate and prognosis, can be greatly improved by the application of medical imaging contrast agents. The development of non-toxic nano-sized contrast agents with stronger imaging ability and longer cycling time through emerging nanotechnology is a hot topic in current research. Herein, the basic applications of such agents to tumor diagnosis of biomedical imaging technologies such as MRI, CT, US, PET and SPECT are summarized, together with some research examples. The nano-sized contrast agents are confirmed to have broad clinical application prospects. Moreover, the future research direction of developing a multi-functional nano-sized platform integrating diagnosis and treatment is proposed.

Key words: nanoparticle, contrast agent, imaging diagnosis, tumor

ZHU Xiaoqi, LIU Junjie, LI Hongxue, ZHOU Zhizhan. Advances in Basic Application of Nano-sized Contrast Agents to Imaging Diagnosis of Tumors[J]. IMAGING SCIENCE AND PHOTOCHEMISTRY, 2021, 39(2): 159-165.

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