IMAGING SCIENCE AND PHOTOCHEMISTRY ›› 2022, Vol. 40 ›› Issue (1): 133-137.DOI: 10.7517/issn.1674-0475.210720

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Study of Abdominal Color Doppler Ultrasound Combined with CA125 in the Diagnosis of Ovarian Serous Tumors

DING Yingchun1, BAO Lingling1, YAN Xiaopeng2   

  1. 1. Department of Ultrasound Medicine, Lujiang People's Hospital, Hefei 231501, Anhui, P. R. China;
    2. Department of Ultrasound Medicine, Second Affiliated Hospital of Bengbu Medical College, Bengbu 233017, Anhui, P. R. China
  • Received:2021-07-20 Published:2022-01-11

Abstract: This study discussed the value of abdominal color ultrasound combined with carbohydrate antigen 125 (CA125) in the diagnosis of ovarian serous tumors. A total of 80 cases of ovarian serous tumor patient were selected, including 23 cases of ovarian serous cystadenoma, 30 cases of serous borderline tumor and 27 cases of serous carcinoma, the differences of ultrasound characteristics and serum CA125 in each group were compared. The proportion of cystic solid echo, blood flow distribution and ascites in patients with serous borderline tumor and serous carcinoma was significantly higher than that in patients with ovarian serous cystadenoma (P<0.05), and the proportion of regular shape and clear boundary was significantly lower than that in patients with ovarian serous cystadenoma (P<0.05). The serum CA125 of serous carcinoma patients was (301.45 ±104.42) U/mL, which was significantly higher than that in patients with serous borderline tumor and ovarian serous cystadenoma (P<0.05). The serum CA125 of serous borderline tumor patients was (210.10±98.28) U/mL, which was significantly higher than that in patients with ovarian serous cystadenoma (P<0.05). The specificity, accuracy and positive predictive value of ultrasound combined with serum CA125 in the diagnosis of serous carcinoma were 90.57%, 87.50% and 81.48% respectively, which were significantly higher than those of ultrasound (P<0.05). Abdominal color Doppler ultrasound combined with CA125 has a good value in differential diagnosis of ovarian serous tumor.

Key words: abdominal color Doppler ultrasound, carbohydrate antigen 125, ovarian serous tumor, diagnostic value