The Role of Contrast-enhanced Ultrasound in Puncture Biopsy of Peri-pulmonary Lesions

doi:10.7517/issn.1674-0475.220622

Abstract

Abstract: This paper investigated the application value of ultrasound and contrast-enhanced ultrasound-guided coarse needle biopsy in peripheral pulmonary lesions. 158 patients with peripheral pulmonary lesions diagnosed by CT or MRI were selected as the research objects. They were divided into conventional ultrasound group and contrast-enhanced ultrasound group. The conventional ultrasound group underwent puncture biopsy under the guidance of ordinary ultrasound, while the contrast-enhanced ultrasound group underwent ultrasound contrast examination on the basis of ordinary ultrasound, and then percutaneous puncture biopsy under its guidance. The puncture success rate, the display rate of intrafocal necrosis, the diagnostic accuracy of subtype (classification), the positive rate of epidermal growth factor receptor (EGFR) and the complications after puncture were compared between the contrast-enhanced ultrasound group and the conventional ultrasound group. According to the pathological results, the success rate of contrast-enhanced ultrasound group (100%) was higher than that of conventional ultrasound group (90%), P<0.05. The display rate of necrosis in the contrast-enhanced ultrasound group (46%) was much higher than that in the conventional ultrasound group (21%), P<0.05. The diagnostic accuracy rate of subtype (classification) in the contrast-enhanced ultrasound group (96%) was slightly higher than that in the conventional ultrasound group (94%),the difference was not statistically significant (P>0.05). The positive rate of EGFR in the contrast-enhanced ultrasound group (32%) was lower than that in the conventional ultrasound group (35%),the difference was not statistically significant (P>0.05). Ultrasound and contrast-enhanced ultrasound-guided puncture are of great value in the diagnosis of peripheral lung lesions, and contrast-enhanced ultrasound has more advantages over conventional ultrasound in the relationship between the lesion and the surrounding tissue structure and the blood flow inside the lesion, which can effectively improve the success rate of puncture.

Key words: contrast-enhanced ultrasound, peripheral pulmonary lesions, peripheral lung lesions

ZHU Pengfei, HE Ying. The Role of Contrast-enhanced Ultrasound in Puncture Biopsy of Peri-pulmonary Lesions[J]. IMAGING SCIENCE AND PHOTOCHEMISTRY, 2022, 40(6): 1349-1353.

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