Study of DWI Combined with FLAIR-HVS on Ischemic Penumbra Viability and the Degree of Neurological Deficit in ACI

doi:10.7517/issn.1674-0475.220821

Abstract

Abstract: This paper discussed the value of diffusion weighted imaging (DWI) combined with fluid-attenuated inversion recovery (FLAIR) hyperintense vessel sign (HVS) in evaluating the viability of ischemic penumbra and the degree of neurological deficit in patients with acute cerebral infarction (ACI). 120 patients with ACI were scanned with DWI and FLAIR sequences, apparent dispersion coefficient (ADC) value, relative apparent dispersion coefficient (rADC) value of infarcted area, ischemic penumbra and survivable area were analyzed. ADC values in ischemic penumbra and viable areas were significantly higher than those in infarcted areas (P<0.05), and rADC values in viable areas were significantly higher than those in ischemic penumbra and infarcted areas (P<0.05). The area under ROC curve of viable areas predicted by rADC value was 0.715, P<0.05. The good prognosis rate of patients with HVS-DWI mismatch was significantly higher than that of patients without HVS-DWI mismatch (P<0.05) at 3 months of follow-up. The mismatch ratio of HVS-DWI decreased significantly with the increase of neurological deficit, infarct volume and vascular stenosis (P<0.05). DWI has certain application value in predicting the viability of ischemic penumbra in ACI. HVS-DWI mismatch is related to the degree of neurological deficit, infarct volume, degree of vascular stenosis and prognosis.

Key words: diffusion weighted imaging, fluid-attenuated inversion recovery, hyperintense vessel sign, acute cerebral infarction, ischemic penumbra viability, degree of neurological deficit

FANG Lei, SUN Huiqin, LI Hongfeng. Study of DWI Combined with FLAIR-HVS on Ischemic Penumbra Viability and the Degree of Neurological Deficit in ACI[J]. IMAGING SCIENCE AND PHOTOCHEMISTRY, 2022, 40(6): 1607-1611.

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