SENSITIZED PHOTOOXIDIZATION OF CHOLESTEROL AND L-CYSTEINE BY PHTHALOCYANINE SULFONATES

doi:10.7517/j.issn.1674-0475.1991.01.36

Abstract

Abstract: Phthalocyanine sulfonates (H2SPC). chlorogallium phthalocyanine (CaClSPC) and chlor-oaluminum phthalocyanine (A1C1SPC) have been synthesized and their sensitized photooxid-ation of cholesterol and L-cysteine have been studied. Both aggregation of dyes and pH value of the solution affect the reaction rate. The results of enhancement of photooxidation rate observed when D₂O was used as the solvent and the quenching effect of NaN₂ indicate that sensitized photooxidation proceeds mainly via Type Ⅱ mechanism (involving singlet oxygen 2O2).

Key words: Phthalocyanine, sensitized photooxidization, cholesterol, L-cysteine, photo-dynamic therapy

SONG JIN-HUA, AN JIN-YI, XU HUI-JUN. SENSITIZED PHOTOOXIDIZATION OF CHOLESTEROL AND L-CYSTEINE BY PHTHALOCYANINE SULFONATES[J]. Imaging Science and Photochemistry, 1991, 9(1): 36-43.

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