Imaging Science and Photochemistry ›› 2018, Vol. 36 ›› Issue (2): 117-129.DOI: 10.7517/j.issn.1674-0475.2018.02.001

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Photo-responsive Surfaces for Cell Adhesion

HAO Yuwei1,3, LIU Hongliang2,3, WANG Shutao2,3   

  1. 1. Key Laboratory of Green Printing, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, P. R. China;
    2. CAS Key Laboratory of Bio-inspired Materials and Interfacial Science, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing 100190, P. R. China;
    3. University of Chinese Academy of Sciences, Beijing 100049, P. R. China
  • Received:2017-07-06 Revised:2017-08-28 Online:2018-03-15 Published:2018-03-15

Abstract: Responsive process of photo-responsive molecules can be modulated by external stimuli, like wave length, light intensity and exposure time. Recently, smart surfaces based on photo-responsive molecules (such as azobenzene, spiropyran and their derivatives) have been adopted to manipulate cell adhesion. Photo-isomerization of these molecules can change the physicochemical properties of surfaces, which can induce cell adhesion and detachment. Design of photo-controlled surfaces provides a novel strategy to investigate cell adhesion, migration, and diagnosis.

Key words: photo-responsive surfaces, cell adhesion, azobenzene, spiropyran