The Value of SWE Combined with Urinary Exfoliative Cytology Detection in the Identification of Bladder Urothelial Carcinoma Grades

doi:10.7517/issn.1674-0475.221022

Abstract

Abstract: This study investigated the application of shear wave elastography (SWE) combined with the urinary exfoliated cells detection in the diagnosis and grade judgment of bladder urothelial carcinoma. 87 patients with bladder urothelial carcinoma confirmed by pathological examination were selected as the case group, and 85 patients with simple urothelial hyperplasia were selected as the control group. The routine ultrasound characteristic parameters, SWE parameters, and fluorescence in situ hybridization (FISH) detection results of urinary exfoliated cells were compared between the two groups of patients, and the case groups were stratified according to the pathological grading results. Compared the ultrasound parameters of the case group and the control group, the rich lesion blood flow characteristics, the internal echo inhomogeneous rate, the multiple tumor lesion rate, and the surface roughness rate in the case group were significantly higher than those in the control group (P<0.05). The lesion SWE parameters Emax, Emean and Emin of the case group were significantly higher than those of the control group (P<0.05), the positive rate of FISH in the case group was higher than that in the control group (P<0.05). In patients with high-grade bladder urothelial carcinoma, the blood flow enrichment rate and the surface feature roughness rate of lesions were significantly higher than those in patients with low-grade lesions (P<0.05). The SWE parameters Emax, Emean and Emin of patients with high-grade bladder urothelial carcinoma were significantly higher than those of patients with low-grade lesions (P<0.05). The positive rate of FISH in patients with high-grade bladder urothelial carcinoma was higher than that in low-grade patients (P<0.05). The detection of SWE and urinary exfoliated cells has high clinical value in the diagnosis of bladder urothelial carcinoma and the assessment of lesion grade.

Key words: shear wave elastography, urine exfoliated cells, bladder urothelial carcinoma, ultrasound, fluorescence in situ hybridization

YANG Beibei, XU Jinzhi, ZHENG Xiaoju. The Value of SWE Combined with Urinary Exfoliative Cytology Detection in the Identification of Bladder Urothelial Carcinoma Grades[J]. IMAGING SCIENCE AND PHOTOCHEMISTRY, 2023, 41(1): 53-58.

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