Abstract: This study investigated the value of color doppler ultrasound in the diagnosis of neonatal hypoxic-ischemic encephalopathy. 92 neonates with hypoxic-ischemic encephalopathy were selected, and the parameters of color doppler ultrasound were observed and analyzed. The cerebral artery Vs, Vd and Vm of moderate to severe children were significantly lower than those of mild children (P<0.05), while RI was significantly higher than that of mild children (P<0.05). The areas under the ROC curve of Vs, Vd, Vm and RI in the diagnosis of moderate to severe children were 0.693、0.810, 0.835 and 0.800, respectively, P<0.05. The body weight, Vs, Vd and Vm of children with poor prognosis were significantly lower than those of children with good prognosis (P<0.05), and the proportion of acidosis, moderate to severe disease and RI were significantly higher than those of children with good prognosis (P<0.05). Logistic regression analysis showed that color doppler ultrasound parameters were the risk factors for poor prognosis of neonatal hypoxic-ischemic encephalopathy (P<0.05). The color doppler ultrasound parameters of neonates with hypoxic-ischemic encephalopathy are obviously abnormal, which is related to the degree of illness and prognosis, and has certain application value in the diagnosis of moderate and severe children.

Key words: color doppler ultrasound, neonates, hypoxic ischemic encephalopathy, degree of illness, prognosis