Table of Content

15 July 2021, Volume 39 Issue 4

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2021, 39(4):  0-0. 

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Review and Articles

Application of Indocyanine Green in Bioimaging and Medical Engineering

ZHOU Qiaoyu, XU Jiajia, LIU Min, MA Xin, HUANG Yurou, WU Yandong, CHEN Qiong, YIN Jun

2021, 39(4):  487-491.  DOI: 10.7517/issn.1674-0475.210110

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Indocyanine green (ICG), a cationic cyanine dye, has the advantages of low toxicity, high affinity and near-infrared emission. Therefore, as a kind of near-infrared organic fluorescent dye which can be used in clinical medicine, it has been widely applied in biological imaging, disease diagnosis and other fields. In this paper, the clinical application and tumor diagnosis and treatment of indocyanine green were discussed, and the relevant information about ICG was comprehensively introduced through examples.

Effect of Light Irradiation on the Surface Properties of the Surfactant Having Fluorine

WANG Kun, JIANG Xiaoming

2021, 39(4):  492-496.  DOI: 10.7517/issn.1674-0475.210112

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A partially fluorinated surfactant, CF-S, was prepared using p-trifluoromethyl aniline as the starting material. Its UV-Vis spectrum was measured. The photoisomerization of CF-S was studied. The surface tension of the CF-S solution was measured. The corresponding physicochemical parameters were calculated. The properties of CF-S were compared with those of CH-S, a surfactant without fluorine. It was found that the surface activity of CF-S was significantly stronger than that of CH-S. After UV light irradiation, CF-S showed higher cmc and γ_cmc, lower Г_max and greater A_min. The wettability of CF-S to quartz was measured.The fluorinated surfactant can improve the hydrophobicity of the quartz surface. The contact angle of CF-S on the quartz surface was decreased by UV light irradiation. So the wettability of CF-S was increased. The Zeta potential of the quartz particles was measured in the CF-S solution. After adding CF-S into the solution, the Zeta potential of the quartz particles was increased. After UV irradiation, the Zeta potential of quartz was decreased. Some adsorbed surfactants were desorbed from the quartz surface.

Fully Suspended and Broad Spectral Photodetectors Based on Self-supported MoS₂-RGO-MoS₂ Composite Film

WANG Chenfeng, CAO Yang

2021, 39(4):  497-503.  DOI: 10.7517/issn.1674-0475.210106

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The broad spectral photodetector is designed to obtain the electromagnetic wave information of ultraviolet, visible and infrared bands, which are emitted or reflected by the target to accurately identify and analyze the target in various environments. The broad spectral photodetectors are widely used in imaging, medical diagnosis, remote sensing, night vision, environmental monitoring, and artificial intelligence fields. In this paper, a suspended MoS₂-RGO-MoS₂ photodetector is designed and fabricated by combining the high-efficiency and broad-spectrum optical absorption characteristics of MoS₂ with the high-efficiency transport characteristics of RGO. In the unique structure of MoS₂-RGO-MoS₂, the MoS₂ on the upper surface plays a role to absorb incident light, and the MoS₂ on the lower surface is able to absorb the transmitted light. This elegant design endows the detector with high-efficiency light capture and improved responsivity. The comparative study of MoS₂-RGO-MoS₂ photodetector and RGO photodetector shows that the responsivity of MoS₂-RGO-MoS₂ photodetector is significantly higher than that of RGO photodetector in a wide spectral range from UV (375 nm) to NIR (1550 nm). The highest responsivity of MoS₂-RGO-MoS₂ photodetector can reach 1006 mA/W and this is of great significance to the practical application of the detector.

Development of Photoresist Resins and Their Synthesis Methods for Extreme Ultraviolet Lithography

WEN Shuai, LIU Qiang

2021, 39(4):  504-511.  DOI: 10.7517/issn.1674-0475.210122

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Extreme ultraviolet lithography (EUVL) has become the most productive technology to achieve the manufacturing of integrated circuit at 22 nm node and beyond. In this paper, the structural characteristics of the EUV photoresist resins and their effects on photolithographic properties were introduced. Based on the structures and synthesis methods of photoresists, the polymeric synthesis methods of chemically and non-chemically amplified EUV resists were mainly reviewed. Finally, the direction of structural design for EUV photoresist in the future was forecasted.

Comparative Analysis of Benign and Malignant Properties of Breast Molybdenum Target and Contrast-enhanced Ultrasonography in Differential Diagnosis of Breast Non-mass-like Lesions

ZHAO Ting, JIANG Shiliang

2021, 39(4):  512-516.  DOI: 10.7517/issn.1674-0475.201113

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The purpose of this study was to explore the value of mammography and contrast-enhanced ultrasonography in the diagnosis of breast non-mass-like lesions (NMLE). A total of 110 cases of NMLE were selected for mammography and contrast-enhanced ultrasonography, and were compared with pathological results. The results show that 87 cases of malignant lesions and 23 cases of benign lesions were confirmed by pathology. The mammography of malignant lesions showed the proportion of calcification, asymmetry or disorder, irregular high density were significantly higher than that in benign lesions (P<0.05). There was significant difference in the contrast-enhanced manifestations of malignant and benign lesions (P<0.05). The sensitivity, accuracy and negative predictive value of contrast-enhanced ultrasound in the diagnosis of benign and malignant lesions were significantly higher than those of mammography (P<0.05). The results showed that compare with mammography, contrast-enhanced ultrasonography has a higher value in differentiating benign and malignant lesions of NMLE, which is worth clinical use.

The Value of MRI in the Diagnosis of Lumbar Instability

WANG Shaofeng, MENG Xiaoqing, ZHAO Yulong, YUAN Qian, WEI Yundong

2021, 39(4):  517-521.  DOI: 10.7517/issn.1674-0475.201123

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The purpose of this study was to investigate the value of magnetic resonance imaging (MRI) in the diagnosis of lumbar instability, including the proportion of paravertebral muscle fat infiltration, cross-sectional area and lumbar lordosis. Eighty-seven patients with degenerative lumbar instability were selected as observation group, and 50 healthy subjects were selected as the control group. MRI examination was performed in both groups, the proportion, cross-sectional area and lumbar lordosis of paravertebral muscle fat infiltration were compared between the two groups. The results show that the cross-sectional area of the multifidus muscle and the percentage of fat infiltration in erector spinae in the observation group were significantly lower than those in the control group (P<0.05). The percentage of fat infiltration and lumbar lordosis in the observation group were significantly higher than those in the control group (P<0.05). The MRI parameters of patients with different segmental instability and frymoyer classification in the observation group were statistically significant (P<0.05). The area under the ROC curve of the cross-sectional area and the proportion of fat infiltration of the multifidus muscle in diagnosing multisegment instability were big enough (P<0.05), as well as the fat infiltration proportion in erector spinae and lumbar lordosis. This study confirmed that proportion of fat infiltration and cross-sectional area in paravertebral muscles on MRI have certain application value in the diagnosis of lumbar instability, as well as the lumbar lordosis, which has the highest diagnosis value.

Application Value of 256 Slice Spiral CT Perfusion Imaging Parameters in the Diagnosis of Gliomas

ZENG Ling, LIANG Chuan, CHEN Xi, GONG Zhiwei

2021, 39(4):  522-525.  DOI: 10.7517/issn.1674-0475.201206

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The purpose of this study was to investigate the application value of 256 slice spiral CT perfusion imaging parameters in the diagnosis of glioma. A total of 91 patients with glioma were selected as research subjects. All patients were examined with 256 slice spiral CT perfusion imaging, and the expression of vascular endothelial growth factor (VEGF) was detected by immunohistochemistry. Compared with the contralateral normal brain tissue, the cerebral blood flow (CBF), cerebral blood volume (CBV) and capillary surface permeability (PS) in the lesion area were significantly higher (P<0.05). The CT perfusion imaging parameters CBF, CBV, PS and optical density values of VEGF in high-grade lesions were significantly higher than those of low-grade lesions (P<0.05). There was a positive correlation between CBF, CBV and the optical density of VEGF expression (P<0.05). The AUC of CBF, CBV and PS in differentiating high-grade lesions were 0.885, 0.877 and 0.792 (P<0.05). 256 slice spiral CT perfusion imaging parameters have good application value in the differential diagnosis of low and high-grade gliomas, and are correlated with VEGF expression, which can indirectly reflect angiogenesis.

Analysis of Correlation between SWE Imaging Technical Parameters and Peak, Tp, MTT and Combined Diagnostic Value of Thyroid Benign and Malignant Nodules

ZHAO Hengda, WANG Yi

2021, 39(4):  526-532.  DOI: 10.7517/issn.1674-0475.201207

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The purpose of this study is to explore the correlation between shear wave elastography (SWE) technical parameters and contrast-enhanced ultrasound (CEUS) parameters of benign and malignant thyroid nodules, and the value of combined diagnosis of benign and malignant thyroid nodules by SWE and CEUS. Fifty-one patients with malignant thyroid nodules in our hospital were selected as the malignant group, and 63 patients with benign thyroid nodules were selected as the benign group. All of them underwent SWE and CEUS examinations. The diagnostic value was analyzed. The results of the study found that E_min, E_mean, E_max and Peak was negatively correlated and positively correlated with Tp (P<0.05); the AUC value of the combined diagnosis of malignant thyroid nodules by SWE and CEUS was 0.952, which was greater than any single index diagnosis (P<0.05); E_min, E_mean, E_max, Tp, MTT is positively correlated with clinical stage, nodule size, and calcification, and negatively correlated with the degree of differentiation. Peak is negatively correlated with clinical stage, nodule size, and calcification, and positively correlated with the degree of differentiation (P<0.05). These results can be It is confirmed that the combination of SWE technology and CEUS in the diagnosis of thyroid benign and malignant nodules is of high value, and plays an important role in guiding clinical development of treatment plans.

The Value of SWE Parameter Elastic Modulus in the Diagnosis of Axillary Lymph Node Metastasis in Breast Cancer

CHEN Jia, LI Ling

2021, 39(4):  533-537.  DOI: 10.7517/issn.1674-0475.201208

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The purpose of this study was to explore the value of real-time shear wave elastography (SWE) parameter modulus of elasticity in the diagnosis of axillary lymph node metastasis of breast cancer. A total of 240 breast cancer patients were selected for SWE examination, all patients underwent surgical resection and axillary lymph node (ALN) resection. The SWE images of the ALN positive group showed sclerosing sign, black hole sign, uneven distribution of the lesion elasticity, non-uniform abnormal color inside the lesion, and red of color hardness spectrum were significantly higher than those of the ALN negative group (P<0.05). The maximum value of elastic modulus (E_max), mean value of elastic modulus (E_mean), standard deviation (SD) and ratio of the average elastic modulus (E_ratio) in the ALN positive group were significantly higher than those in the ALN negative group (P<0.05). The results of Logistic regression analysis showed that non-uniform abnormal color inside the lesion, E_max, E_mean and E_ratio were the influencing factors for ALN metastasis in breast cancer patients (P<0.05). The value of the elastic modulus of SWE parameter has a certain diagnostic value in ALN metastasis of breast cancer, which is worth clinical use.

Changes of Ultrasound Multimodal Scores and Blood Flow Parameters in Patients with Unexplained Recurrent Spontaneous Abortion and Their Combined Predictive Value

WU Xinrong, ZHENG Ying

2021, 39(4):  538-543.  DOI: 10.7517/issn.1674-0475.201211

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The purpose of this study was to investigate the changes of ultrasound multimodal scores and blood flow parameters in patients with unexplained recurrent spontaneous abortion and their combined predictive value.86 cases of early pregnancy patients with unexplained recurrent spontaneous abortion (URSA) were selected. According to whether miscarriage occurred within 12 weeks of gestation, they were divided into non-abortion group (62 cases) and miscarriage group (24 cases). And 86 pregnant women with normal early pregnancy during the same period were selected as the control group. Endometrial ultrasound multimodal score was detected, as well as uterine artery blood flow parameters including pulsatility index (PI), resistance index (RI), peak systolic velocity end diastolic velocity (S/D). It was found that ultrasound multimodal scores, PI, RI, S/D were significantly related to β-HCG, progesterone and miscarriage in early pregnancy patients of URSA. The AUC for combined predicting 538miscarriage in early pregnancy patients of URSA was 0.886, the 95%CI was 0.806 to 0.965. The sensitivity was 83.33%, and the specificity was 83.87%, which was better than the individual prediction of each index. It can be seen that ultrasound multimodal scores and blood flow parameters are abnormal in URSA patients. And the combined prediction for miscarriage has a good value, which can provide effective information for early clinical intervention.

Study on the Correlation between Carotid Artery Vulnerable Plaque and ACR and ALBU in High-Risk Population of Stroke Based on Carotid Ultrasound Screening

ZHANG Xiaoyan, SONG Jing, WU Xiaoming, CAI Dongping, ZHU Liangyuan, YAN Qiong, HAN Wen

2021, 39(4):  544-549.  DOI: 10.7517/issn.1674-0475.201215

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The purpose of this study was to explore the correlation between carotid artery ultrasound screening of carotid artery vulnerable plaque and urinary microalbumin/creatinine (ACR) and urinary microalbumin (ALBU) in people at high risk of stroke. According to the carotid ultrasound examination, 307 selected patients with high risk of stroke were divided into: 112 cases without carotid plaque, 45 cases with stable carotid plaque and 150 cases with carotid artery vulnerable plaque. The study found that there were significant differences in the proportions of age ≥ 60 years old, the proportion of family history of stroke, and the comparison of carotid artery intima-media thickness (IMT), ACR, and ALBU levels (P<0.05). IMT and ACR and ALBU are positively 544 correlated (P<0.05). Age, family history of stroke, IMT, ACR, and ALBU are all influencing factors of carotid plaque in people at high risk of stroke (P<0.05). IMT, ACR, and ALBU are combined in the diagnosis of carotid plaque and the differential diagnosis of vulnerable plaque have high efficiency. These results can confirm that IMT is positively correlated with ACR and ALBU in high-risk populations of stroke. Early combined IMT, ACR, and ALBU examination can assist clinical diagnosis of carotid plaque and differential diagnosis of vulnerable plaque.

Diagnostic Value and Correlation Analysis of Uterine Artery Blood Flow Doppler Parameters Combined with Serum SDC-1 and VEGF-A in Endometriosis

LU Xiangzhang, DENG Yanjun

2021, 39(4):  550-555.  DOI: 10.7517/issn.1674-0475.201219

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The purpose of this study was to investigate the diagnostic value of Doppler parameters of uterine artery combined with serum syndecan-1 (SDC-1), vascular endothelial growth factor-A (VEGF-A) in the diagnosis of endometriosis (EMS) and the relationship between them and clinical pathological parameters. One hundred and two patients with endometriosis (EMS) were selected as the study group, and 102 patients with abdominal mass but not EMS were selected as control group. The results showed that the Doppler parameters of uterine artery blood flow (PSV, EDV, RI, PI), serum SDC-1, VEGF-A were significantly correlated with EMS, PSV EDV was negatively correlated with serum SDC-1 and VEGF-A, RI and PI were positively correlated with serum SDC-1 and VEGF-A, and AUC of EMS was 0.925 for combined diagnosis of each index, and the best sensitivity and specificity were 80.39% and 90.20%, respectively. These results can confirm that the combination of Doppler parameters of uterine artery, serum sdc-1 and VEGF-A has a high value in EMS diagnosis.

Diagnostic Value of Color Doppler Flow Parameters in Fetal Growth Restriction

MA Nan, CHEN Jing, LI Yuanyuan

2021, 39(4):  556-559.  DOI: 10.7517/issn.1674-0475.201102

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The purpose of this study was to investigate the diagnostic value of the blood flow parameters by color Doppler flow imaging (CDFI) in late pregnancy with fetal growth restriction (FGR). A total of 110 cases of third trimester pregnant women with FGR were selected as observation group, and 110 cases of normal pregnant women in the third trimester were selected as the control group. The differences in CDFI blood flow parameters between the two groups were compared. The experimental results showed that,compared to the control group, the PI, RI and S/D of umbilical artery in the observation group was higher. The PI, RI and S/D of the middle cerebral artery in the observation group were significantly lower than those in the control group (P<0.05). The end systolic reflux velocity (ESRV) of aortic arch isthmus in the observation group was significantly higher than that in the control group (P<0.05). The area under the ROC curve of umbilical artery PI, RI and S/D, middle cerebral artery PI, RI and S/D, and ESRV in diagnosing FGR, the area under ROC curve of middle cerebral artery PI was the largest. CDFI blood flow parameters have certain value in the diagnosis of FGR.

The Characteristics of BND, V-BN-S Parameters in Patients with SUI after Natural Delivery Diagnosed by Transvaginal Ultrasound and the Changes before and after Rehabilitation Treatment

JIANG Xiaohua, CHEN Huijuan, LU Xiaoer

2021, 39(4):  560-563.  DOI: 10.7517/issn.1674-0475.201120

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The characteristics of bladder neck movement (BND), bladder neck position (V-BN-S), resting bladder neck position (R-BN-S), and urethral rotation angle (UR) in patients with stress urinary incontinence (SUI) after natural delivery and the changes before and after rehabilitation treatment were investigated. A total of 110 SUI patients after natural delivery were selected as the observation group and 100 cases without SUI after natural delivery were selected as the control group. The BND,V-BN-S,R-BN-S and UR were measured by transvaginal ultrasound. The BND and UR in the observation group were significantly higher than those in the control group, V-BN-S and R-BN-S were significantly lower than those in the control group (P<0.05).The BND and UR of severe patients in the observation group were significantly higher than those in mild and moderate patients, V-BN-S and R-BN-S were significantly lower than those in mild and moderate patients (P<0.05).The BND and UR of the observation group after rehabilitation treatment were significantly lower than those before treatment, while V-BN-S and R-BN-S were significantly higher than before treatment (P<0.05). The condition of SUI patients in the observation group was significantly improved after rehabilitation treatment.

MSCT Findings and Clinical Significance of Spinal Tuberculosis Patients with Incomplete Paralysis

ZHANG Yali, LUO Xiaobo, ZHAO Qian

2021, 39(4):  564-568.  DOI: 10.7517/issn.1674-0475.201209

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The purpose of this study was to investigate the multi-slice spiral CT (MSCT) imaging manifestations and clinical significance of spinal tuberculosis patients with incomplete paralysis before operation. 72 patients (observation group) with incomplete paralysis before spinal tuberculosis surgery in our hospital were selected, including Frankel spinal cord injury classification: 24 cases of grade B, 27 cases of grade C, and 21 cases of grade D, and 90 cases of spinal tuberculosis patients with normal muscle strength were selected as the control group, and the differences of MSCT imaging features between the two groups were analyzed and compared. In the observation group, the proportion of three or more vertebral injuries and the distribution proportion of the diseased vertebral chest segment and above were significantly higher than those in the control group (P<0.05). In the observation group, the ratio of osseous spinal canal incomplete, total vertebral height loss ≥1 vertebral body, paravertebral abscess and compression object compression vertebral canal, compression foramina ratio and kyphosis Cobb Angle were significantly564 higher than those in the control group (P<0.05). In the observation group, the proportion of osseous spinal incomplete in Frankel grade B patients were higher than that in Grade C and D patients (P<0.05). In the observation group, the ratio of paravertreal abscess and compression material to compress vertebral canal, the ratio of compression foramina and kyphosis Cobb Angle in Frankel grade B patients were higher than those in Grade D patients (P<0.05). Compared with spinal tuberculosis with normal muscle strength, MSCT images of spinal tuberculosis patients with preoperative paraplegia are different, and there are also certain differences among different Frankel grades.

Clinical Application of SMI Technology in Detecting Neovascularization in Carotid Plaque

WANG Xiangzhu, WANG Lin, LU Ruigang, YU Zexing

2021, 39(4):  569-573.  DOI: 10.7517/issn.1674-0475.201210

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This study explored the clinical value of superb microvascular imaging (SMI) in detecting neovascularization in carotid atherosclerotic plaque. A total of 100 patients with carotid atherosclerosis diagnosed by color Doppler carotid ultrasound were selected as the research objects. All the included subjects were examined by SMI and contrast-enhanced ultrasound (CEUS). The results of CEUS were used as the criteria to calculate the consistency between SMI test results and CEUS results. The average thickness of hypoechoic plaques detected by carotid color Doppler ultrasound was (3.22±1.07) mm, the average patch length was (11.60 ±3.31) mm; the average thickness of mixed echo plaques was (3.50 ±1.21) mm, the average patch length was (17.32±4.16) mm, the consistency kappa value between SMI detection grading and CEUS grading was 0.516, P=0.000, Spearman R=0.704, P=0.000, SMI and CEUS had high consistency and correlation. SMI has high consistency and correlation with CEUS results in detecting neovascularization in carotid atherosclerotic plaques, which can be used as a noninvasive, rapid and convenient detection method.

Multi-slice Spiral CT in the Diagnosis of Partial Malformation of Large Vessels in Children with Congenital Heart Disease

TU Nana, ZHOU Ling

2021, 39(4):  574-578.  DOI: 10.7517/issn.1674-0475.201220

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The diagnostic value of multi-slice spiral CT (MSCT) in the diagnosis of large vascular malformations in children with congenital heart disease. One hundred and twenty-five children with congenital heart disease confirmed by surgery in our hospital were selected as the research objects, of which 41 were children with congenital heart disease with partial malformation of large vessels, and the other 84 were children with congenital heart disease with abnormal heart structures. The imaging data of 125 children with multi-slice spiral CT were retrospectively analyzed, and the consistency between MSCT and its diagnosis results was statistically analyzed. MSCT has a sensitivity of 92.68% and a specificity of 94.05% in the differential diagnosis of congenital heart disease and intracardiac congenital heart disease with partial malformation of large vessels. The differential diagnosis sensitivity of internal congenital heart disease was 73.17%, specificity was 90.48%, MSCT is a non-invasive method for diagnosing partial malformations of large vessels in children with congenital heart disease, which has higher sensitivity than cardiac ultrasound.

Correlation Analysis of Quantitative Dynamic Contrast-Enhanced MRI and Serum IL-10, IL-12 Expression in Patients with Glioma

LIU Tiefang, ZANG Xiao, ZHANG Dekang, HU Jianxing, LI Meng, WANG Yonghao

2021, 39(4):  579-583.  DOI: 10.7517/issn.1674-0475.201212

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The purpose of this study was to investigate the correlation between quantitative dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) and the expression of serum interleukin-10 (IL-10) and interleukin-12 (IL-12) in patients with glioma. In this study, 150 patients with glioma were included as the observation group, including 68 cases of low-grade glioma and 82 cases of high-grade glioma, as well as 100 healthy patients as control group. The serum IL-10 and IL-12 levels of the two groups were detected, and the observation group was given MRI dynamic contrast enhancement scan. Serum IL-10 and IL-12 in the observation group were significantly higher than those in the control group (P<0.05). In the observation group, the volume transport constant (K^trans), rate constant (K_e) and extracellular volume fraction (V_e) of high-grade glioma patients were significantly higher than those of low-grade glioma patients (P<0.05). The serum IL-10 and IL-12 levels of patients with high-grade glioma in the observation group were significantly higher than those of patients with low-grade glioma (P<0.05). K^trans was positively correlated with IL-10 and IL-12 (P<0.05). The area under the high grade ROC curve of K^trans, K_e, V_e combined with 579 IL-10 and IL-12 glioma was 0.954, which was significantly higher than that of other indexes (P<0.05). MRI parameter K^trans is positively correlated with serum IL-10 and IL-12 in patients with glioma, and has certain application value in differentiating low-grade and high-grade gliomas.

Comparison of Pulmonary Characteristics and Diagnostic Value of X-ray and HRCT in Children with Acute Mycoplasma Pneumoniae Pneumonia

ZHAO Lanhua, YANG Shuhui, MA Lin

2021, 39(4):  584-588.  DOI: 10.7517/issn.1674-0475.210118

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The purpose of this study is to investigate the lung characteristics and diagnostic value of X-ray and high-resolution CT (HRCT) in children with mycoplasma pneumoniae pneumonia (MPP). One hundred and twenty children with MPP who were treated were selected and divided into X-ray group (n=70) and HRCT group (n=50). The X-ray group received chest X-ray examination, and the HRCT group received HRCT examination. The MPP diagnosis rate of HRCT group was 92.00%, which was higher than that of X group (P<0.05). The X-ray images were mainly interstitial infiltration, followed by hilar shadow enlargement, lung texture thickening and increase, etc. HRCT examination mainly consisted of non-uniform high-density lung consolidation shadows, including lobular consolidation shadows, segmental consolidation shadows and macrophylla consolidation shadows. In the HRCT group, FEF₂₅ and FEF₇₅ accounted for the projected value of macrophylla consolidation shadows were significantly lower than lobular consolidation and segmental consolidation (P<0.05). The proportion of FEF₇₅ in children with segmental consolidation shadow was lower than that of lobular consolidation shadow (P<0.05). HRCT has a good application value in the diagnosis of MPP, and the consolidation shadow of HRCT has a certain relationship with lung function.

The Value of Parameters of CT Bone Imaging in the Diagnosis of Posterior Ligamentous Complex Injury in Thoracolumbar Fracture and the Analysis of Risk Factors

ZHU Siguang, SUN Tao

2021, 39(4):  589-594.  DOI: 10.7517/issn.1674-0475.201202

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A total of 380 patients with thoracolumbar fracture were selected as the research objects, which were 168 patients with thoracolumbar fractures and posterior ligamentous complex (PLC) injuries as the observation group, and 212 patients without PLC injuries a the control group. Through statistical comparison, it was found that the load-sharing classification system (LCS) score, thoracolumbar injury classification and severity (TLICS) score, Cobb angle, SIEA, LK, and IISD were significantly different between the two groups (P<0.05). The sensitivity of the diagnosis of PLC injury in thoracolumbar fractures through the combination of CT bone imaging parameters was 72.41% and the specificity was 87.33%. The SIEA, LK and IISD of patients with poor prognosis before and 3 days after operation were higher than those with good prognosis (P<0.05). The AUC of SIEA, 589 LK, and IISD 3 days after surgery were higher than those of preoperatively, and the AUC of combined prediction of PLC injury in thoracolumbar fractures was the highest, which was 0.869. The best sensitivity and specificity were 72.62% and 87.26%, respectively. Therefore, it can be considered that SIEA, LK, and IISD are the risk factors for PLC injury of thoracolumbar fractures, and the combination of the three can provide references for clinical diagnosis of PLC injury of thoracolumbar fractures and prediction of prognosis.

Preoperative Rapid Ultrasound Evaluation and Intraoperative Transesophageal Echocardiographic Monitoring for the Clinical Guidance of Anesthesia in Critically Ill Patients

YU Xuan, LU Bin, LI Qiang, CAO Lu, FAN Bin

2021, 39(4):  595-600.  DOI: 10.7517/issn.1674-0475.210207

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The purpose of this research was to investigate whether the technology has clinical significance in critically ill patients. A total of 60 critically ill patients were randomly divided into the control group (based on the experience assessment of anesthesiologists) and the observation group (based on the assessment of ultrasound and transesophageal echocardiography monitoring).The outcomes were fluid volume, type and dosage of vasoactive drugs intraoperative, and the time of extubation after operative. The results showed that the types of vasoactive drugs in the observation group were significantly more than those in the control group (P<0.05). The reduction of vasoactive drugs patients in the observation group was significantly more than those in the control group (P<0.05).In terms of blood pressure, the observation group was significantly higher than that of the control group when leaving the operation room (P<0.05).For the urine volume, observation group was significantly higher than that of control group during the operation (P<0.05). The extubation time in the observation group was significantly shorter than that in 595the control group (P<0.05). Therefore,the preoperative rapid ultrasound evaluation and intraoperative transesophageal echocardiographic monitoring had clinical significance for the clinical guidance of anesthesia in critically ill patients.

Evaluation Value of TPUS Examination on PFD Occurrence in Patients after Hysterectomy

JI Runyan, HE Bosheng, WU Jing

2021, 39(4):  601-605.  DOI: 10.7517/issn.1674-0475.201218

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This paper aims to analyze the value of transperineal ultrasound (TPUs) in the assessment of pelvic floor dysfunction (PFD) after hysterectomy. One hundred and fifty-seven patients who underwent total hysterectomy were selected. According to whether PFD occurred after operation, they were divided into two groups: 103 patients without PFD and 54 patients with PFD. All patients underwent TPUs examination. The results showed that compared with the non PFD group, the bladder downward distance, rectum downward distance, vaginal fornix downward distance, posterior angle of urethra, left and right diameter, anteroposterior diameter, area and perimeter of levator ani hiatus in PFD group increased, and the urethral inclination angle decreased (P<0.05). There was no significant difference in levator ani thickness between the two groups (P>0.05). Compared with transperineal two-dimensional, three-dimensional and four-dimensional ultrasound examination alone, the diagnostic value of three combined examinations was higher (P<0.05). In conclusion, it is found that patients with PFD after hysterectomy, TPUs examination has ideal diagnostic value for PFD, which can be used for clinical diagnosis and evaluation of PFD after hysterectomy.

Application Value of Enhanced CT in Staging and Prognosis Evaluation of Esophageal Carcinoma

CHEN Jiang, WU Tao

2021, 39(4):  606-610.  DOI: 10.7517/issn.1674-0475.201119

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The purpose of this study was to investigate the application value of enhanced CT in the stage and prognosis evaluation of esophageal cancer. A total of 252 cases of esophageal cancer patients were selected for enhanced CT scan with 16-slice CT scanner. The diagnostic accuracy of enhanced CT in the T3 and T4 stages of esophageal cancer was higher than that in the T1 and T2 stages (P<0.05). There was no significant difference in the diagnostic accuracy of N0 and N1 stage by enhanced CT in patients with esophageal cancer (P>0.05). During the follow-up to October 2017, the short-term efficacy and 2-year local control rate of patients with homogeneous lymph node density were higher than those of patients with low-density and marginal enhanced internal necrosis; the short-term efficacy and 2-year local control rate of patients with low-density were higher than those of patients with marginal enhanced internal necrosis (P<0.05). The short-term efficacy and 2-year local control rate of patients with regular lymph node margin were higher than those with irregular lymph node margin and obvious invasion (P<0.05). It is suggested that enhanced CT plays an important role in the evaluation of preoperative clinical staging of esophageal cancer patients and prognosis of chemotherapy patients, and has guiding significance for the follow-up treatment of patients.

Multi-slice Spiral CT Angiography in the Diagnosis of Diabetic Foot Lower Extremity Artery Disease

ZHANG Yufeng, LIU Yanwu

2021, 39(4):  611-614.  DOI: 10.7517/issn.1674-0475.201203

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The purpose of this study was to explore the application of multi-slice spiral CT (MSCT) angiography in the diagnosis of diabetic foot (DF) lower limb arterial disease. A total of 78 patients with DF were selected as DF group, 41 patients were mild, 37 were severe, 80 patients with diabetes were selected as control group (DM group), and MSCT angiography was used to detect the cross-sectional area of lower extremity artery lumen. The lumen cross-sectional areas of femoral artery, popliteal artery and posterior tibial artery in DF group were significantly smaller than those in DM group (P<0.05); The lumen cross-sectional areas of common iliac artery, femoral artery, popliteal artery, anterior tibial artery, posterior tibial artery, peroneal artery and dorsalis pedis artery in severe patients of DF group were significantly smaller than those of mild patients (P<0.05); There was no significant difference in the cross-sectional area of lower extremity artery in patients of different gender and age of DF group (P>0.05). MSCT angiography can clearly show the arterial lesions of DF lower limbs, and the sectional area of arterial lumen of lower limbs can reflect the severity of the disease.

The Effect of MRI Angiography on the Degree of Carotid Artery Stenosis and Plaque Composition

LI Shuo, GAO Junhua, LIANG Bo, DU Xiaopeng, HUANG Shunxing, ZHANG Huan, DU Lei

2021, 39(4):  615-619.  DOI: 10.7517/issn.1674-0475.201225

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This article explores the value of magnetic resonance (MRI) angiography in judging the degree of carotid artery stenosis and analyzing the composition of plaque in patients with carotid atherosclerosis. A total of 149 patients with carotid atherosclerosis diagnosed in our hospital were selected as the research objects. The patients received MRI angiography, three-dimensional ultrasound (3D-US), and digital subtraction angiography (DSA) within one week. The results showed that the diagnosis of carotid artery stenosis by MRI angiography was highly consistent with DSA.The plaque load parameters of 219 blood vessels were compared. There was no significant difference between the MRI detection of blood vessel wall area, maximum wall thickness, standardized wall index and 3D-US diagnosis results (P>0.05). Only the vascular cavity area was statistically different from the 3D-US results (P<0.05); MRI angiography diagnoses plaque fibrous cap, lipid nucleus, hemorrhage in the plaque, and calcification in the plaque, the coincidence rate with the pathological results is 98.08%, 96.43%, 94.74%, 97.10%, both no 615 statistical difference (P>0.05). There was no statistical difference between the results of MRI angiography in the diagnosis of plaque hardness and pathology (P>0.05). Therefore, MRI angiography has high accuracy in judging the degree of carotid artery stenosis and analyzing the composition of plaque in patients with carotid atherosclerosis, and its results have high consistency with the results of pathology, DSA and 3D-US.

Comparative Analysis of Contrast-enhanced Ultrasound Combined with BI-RADS Grading and Pathological Examination of Breast Cancer

ZOU Fang, WANG Shuang

2021, 39(4):  620-623.  DOI: 10.7517/issn.1674-0475.201107

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The purpose of this study was to investigate the diagnostic value of contrast-enhanced ultrasound combined with BI-RADS grading in breast cancer. 130 cases of suspected breast cancer patients were selected, the routine ultrasound and contrast-enhanced ultrasound were given to analyze the value of contrast-enhanced ultrasound combined with conventional BI-RADS grading in the diagnosis of breast cancer. Among 130 suspected patients, 47 cases were benign, 83 cases of malignant patients; the experimental results showed that: In the ultrasonic imaging features of malignant lesions, the proportion of centripetal enhancement and enhanced lesions enlargement were significantly higher than those of benign lesions (P<0.05). The enhancement start time, time to peak and peak intensity of malignant lesions were significantly lower than those of benign lesions (P<0.05). Compared contrast-enhanced ultrasound and BI-RADS, the sensitivity and negative predictive value and accuracy of combined examination in the diagnosis of breast cancer were higher (P<0.05). This study confirmed that: Contrast-enhanced ultrasound combined with BI-RADS has good clinical value in diagnosing breast cancer, which is worthy of clinical use.