关键词: 阻塞性睡眠呼吸暂停低通气综合征, 自主神经损伤, 动脉顺应性, 超声

Abstract: This article discussed the changes of autonomic nerve injury, arterial compliance ultrasound parameters and their clinical significance in patients with obstructive sleep apnea hypopnea syndrome (SAHS). 140 SAHS patients were selected as the SAHS group, and 70 volunteers without SAHS-related symptoms were selected as the control group. The cardiac function parameters, aortic structure and function parameters, carotid pulse wave propagation speed(PWV1), descending aortic pulse wave velocity(PWV2) of the two groups of subjects were measured by ultrasound, and the Holter parameters changes were detected by electrocardiograph. The measured values of carotid pulse wave velocity (PWV1) and descending aortic pulse wave velocity (PWV2) in the SAHS group were significantly higher than those in the control group (P<0.05). The measured value of total power, very low frequency, and deceleration force (DC) were lower than that of the control group and the difference was significantly (P<0.05). The measured value of the heart rate acceleration force (AC) of the SAHS group was higher than that of the control group (P<0.05). The measured value of sleep-related apnea-hypopnea index(AHI) for SAHS patients was significantly positively correlated with PWV1, PWV2, AC (P<0.05), and the AHI measurement value in SAHS patients was significantly negatively correlated with DC (P<0.05). Patients with SAHS may have autonomic nerve damage and reduced arterial compliance, which are closely related to the severity of sleep apnea.

Key words: obstructive sleep apnea hypopnea syndrome, autonomic nerve injury, arterial compliance, ultrasound