常规超声指标结合HD live技术对单绒毛膜双胎妊娠的预测分析

doi:10.7517/issn.1674-0475.220524

摘要/Abstract

摘要： 探究常规超声检查指标结合HD live技术对单绒毛膜（MC）双胎妊娠的预测价值，均于孕早期行常规超声检查获取胎儿常规超声指标[颈项透明层（NT）厚度、头臀长（CRL）]，进行HD live技术检查获取静脉导管（DV）频谱异常、胎儿脐带异常情况。结果发现，208例（胎儿416例） MC双胎妊娠孕妇中，MC双羊膜囊双胎孕妇胎儿异常率为33.67%，MC单羊膜囊双胎孕妇胎儿异常率为58.33%；胎儿异常组孕早期双胎间NT差异、CRL差异、DV频谱异常率、胎儿脐带异常率均高于胎儿正常组（P<0.05）；孕早期双胎间NT差异、CRL差异及DV频谱异常率、胎儿脐带异常率均与MC双胎妊娠胎儿异常的发生显著相关（P<0.05）；孕早期双胎间NT差异、CRL差异、DV频谱异常率、胎儿脐带异常率单独预测MC双胎妊娠发生胎儿异常的曲线下面积（AUC）均大于0.7，联合预测的AUC最大（0.922）。HD live技术检查MC双胎妊娠的解剖关系显示立体直观，与常规超声检查指标联合预测MC双胎妊娠发生胎儿异常具有良好应用价值。

关键词: 单绒毛膜双胎妊娠, 超声, HD live技术, 胎儿异常, 预测

Abstract: This paper investigated the predictive value of conventional ultrasound indices combined with HD live technique in monochorionic (MC) twin pregnancy. Both conventional ultrasound examinations were performed in early pregnancy to obtain fetal conventional ultrasound indices[nuchal translucency layer (NT) thickness, crown-rump length (CRL)], and HD live technique to obtain ductus venosus (DV) spectral abnormalities and fetal cord abnormalities. The results showed that among 208 cases (416 fetuses) MC twin pregnancies, the fetal abnormality rate was 33.67% in MC double amniotic sac twin pregnancies and 58.33% in MC single amniotic sac twin pregnancies. The fetal abnormal group had higher inter-twin NT difference, CRL difference, DV spectrum abnormality rate and fetal umbilical cord abnormality rate in early pregnancy than the fetal normal group (P<0.05). In the early pregnancy the differences of NT, CRL, DV spectrum abnormalities and fetal umbilical cord abnormalities between twins were significantly associated with the occurrence of fetal abnormalities in MC twin pregnancy (P<0.05). The area under the curve (AUC) of NT differences, CRL differences, DV spectrum abnormalities and fetal umbilical cord abnormalities between twins in early pregnancy predicted the occurrence of fetal abnormalities in MC twin pregnancy alone were greater than 0.7, and the combined predicted AUC was the largest (0.922). The anatomical relationship of the HD live technique for examining MC twin pregnancies showed stereoscopic visualization, and it has good application value for predicting fetal anomalies in MC twin pregnancies when combined with conventional ultrasound indices.

Key words: monochorionic twin pregnancy, ultrasound, HD live technology, fetal abnormalities, prediction

曾秀梅, 梁元豪, 林洋洋, 张茜, 王霞, 朱荷香, 郭红梅. 常规超声指标结合HD live技术对单绒毛膜双胎妊娠的预测分析[J]. 影像科学与光化学, 2022, 40(5): 1029-1033.

ZENG Xiumei, LIANG Yuanhao, LIN Yangyang, ZHANG Qian, WANG Xia, ZHU Hexiang, GUO Hongmei. Prediction Analysis of Conventional Ultrasound Indexes Combined with HD Live Technology in Monochorionic Twin Pregnancy[J]. IMAGING SCIENCE AND PHOTOCHEMISTRY, 2022, 40(5): 1029-1033.

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