Abstract: The aim of this paper was to investigate the value of transvaginal color Doppler ultrasonography (TVCDU), three-dimensional color power angiography (3D-CPA) combined with pulse wave Doppler (PW) in the differential diagnosis of ovarian space-occupying lesions and the evaluation of preoperative staging of malignant lesions. There were 110 patients with ovarian space-occupying lesions who were selected and examined by color Doppler ultrasound, among whom 49 cases were malignant, 61 cases were benign. The peak systolic velocity (PSV) and vascular index (VI) of malignant tumors were significantly higher than those of benign tumors (P<0.05), while resistance index (RI) was significantly lower than that of benign tumors (P<0.05). The proportion of vascular grade Ⅲ of malignant tumors was significantly higher than that of benign tumors (P<0.05), while the proportion of grade Ⅰ was significantly less than that of benign tumors (P<0.05). The proportion of VI and vascular grade Ⅲ in 455 stage Ⅲ patients was significantly higher than that of patients Ⅰ-Ⅱ (P<0.05). The area under ROC curve of RI, VI, vascular classification and combined diagnosis on malignant tumor were 0.794, 0.774, 0.937 and 0.966, respectively. The area under the ROC curve of VI, vascular grading and combined diagnosis of malignant tumor FIGO stage Ⅲ were 0.810, 0.691 and 0.955. In conclusion, TVCDU and 3D-CPA combined with PW have good application value in differentiating the nature of ovarian mass lesions and preoperative staging assessment of malignant lesions.

Key words: color Doppler, three-dimensional color power angiography, pulse Doppler, ovarian space-occupying lesions, benign, malignant, preoperative staging