The Application of DTI and DTT in the Diagnosis of Different Grades of Gliomas

doi:10.7517/issn.1674-0475.210105

Abstract

Abstract: The purpose of this study was to investigate the value of MR diffusion tensor imaging (DTI) and diffusion tensor tractography (DTT) in the diagnosis of glioma of different grade. 84 patients with glioma were selected, the DTI and DTT parameters of low grade and high grade gliomas were compared. The experimental results showed that the damage rate of peritumor white matter fiber bundle in high-grade was significantly higher than that in low-grade (P<0.05). The fractional anisotropy (FA) value of focal parenchymal area in high-grade was significantly higher than that of the low-grade (P<0.05), and the apparent diffusion coefficient (ADC) value was significantly lower than that of the low-grade (P<0.05). The value of fiber density index (FDi) in the peritumor edema area of high-grade was (0.53±0.08), which was significantly lower than that of low-grade (P<0.05). The area under ROC curve of peritumor white matter fiber bundle destruction, FA value and ADC value of lesion parenchyma area, and FDi value of peritumor edema area in differential diagnosis of high grade were 0.857, 0.877, 0.965 and 0.828, respectively (P<0.05). This study confirmed that:DTI and DTT parameters are different in different grades of glioma, which has certain application value in differential diagnosis.

Key words: MR diffusion tensor imaging, diffusion tensor tractography, brain glioma, diagnostic value

WAN Zhengguo, JIA Wen, SUN Yuanyuan, LV Xiaoqing, MENG Kailong. The Application of DTI and DTT in the Diagnosis of Different Grades of Gliomas[J]. IMAGING SCIENCE AND PHOTOCHEMISTRY, 2021, 39(5): 663-666.

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