Value of Carotid Ultrasound Combined with CT and Serum miR-124 and miR-155 in Predicting the Risk of Secondary Cerebral Infarction in Patients with Carotid Stenosis

doi:10.7517/issn.1674-0475.200908

Abstract

Abstract: This study explored the value of carotid ultrasound combined with CT and serum microRNA-124 (miR-124) and microRNA-155 (miR-155) in predicting the risk of secondary cerebral infarction in patients with carotid stenosis.Forty-three patients with carotid stenosis were selected as carotid stenosis group, and 43 normal volunteers were selected as normal group. The expression of miR-124 and miR-155 was detected by RT-PCR. Carotid artery stenosis was examined by carotid ultrasound. The blood vessels in the neck were examined by CT. The results showed that compared with the normal group, the expression of miR-124 and miR-155 in carotid stenosis group was increased (P<0.05).Compared with ultrasound and CT, ultrasound combined with CT had higher accuracy and diagnostic value (P<0.05).It is found that carotid ultrasound, CT, miR-124 and miR-155 have high diagnostic value for carotid artery stenosis, and can be used to predict the risk of secondary cerebral infarction.

Key words: carotid ultrasound, CT, miR-124, miR-155, carotid artery stenosis, secondary cerebral infarction

WANG Shida, WANG Haihong, ZHANG Lina. Value of Carotid Ultrasound Combined with CT and Serum miR-124 and miR-155 in Predicting the Risk of Secondary Cerebral Infarction in Patients with Carotid Stenosis[J]. IMAGING SCIENCE AND PHOTOCHEMISTRY, 2021, 39(2): 246-250.

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