Diagnostic Value of CT Combined with Serum Tumor Markers in Cervical Cancer Patients with Retroperitoneal Lymph Node Metastasis

doi:10.7517/issn.1674-0475.200517

Abstract

Abstract: 122 cases of cervical cancer patients were selected as the research object. According to the results of pathological examination, they were divided into metastasis group (28 patients with retroperitoneal lymph node metastasis) and non-metastasis group (94 patients without retroperitoneal lymph node metastasis). All of them were subjected to CT examination of the whole abdomen and detection of serum tumor markers including carcinoembryonic antigen (CEA), cancer antigen 125 (CA125) and squamous cell carcinoma antigen (SCC-Ag). The results showed that the shortest diameter of CT lymph nodes in the metastatic group was longer than that in the non-metastatic group, and the levels of serum CEA, CA125 and SCC-Ag were higher than those in the non-metastatic group (P<0.05). Serum CEA, CA125, SCC-Ag levels were positively correlated with the shortest diameter of the lymph nodes in the horizontal axis of CT, and the sequence of AUC value for diagnosis of retroperitoneal lymph node metastasis was:CT combined with serum tumor markers > the shortest diameter of CT lateral axis lymph node > SCC-Ag > CEA > CA125. It can provide an objective basis for clinical preoperative evaluation of the presence of retroperitoneal lymph node metastasis.

Key words: CT, cervical cancer, peritoneum, lymph nodes metastasis, carcinoembryonic antigen, squamous cell carcinoma antigen, cancer antigen 125

HAN Qianqian, BU Dao. Diagnostic Value of CT Combined with Serum Tumor Markers in Cervical Cancer Patients with Retroperitoneal Lymph Node Metastasis[J]. Imaging Science and Photochemistry, 2020, 38(6): 982-987.

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